Revolutionary new capabilities for monitoring physical health of humans, machinery, and the processes governing the climate and condition of our entire planet are currently in development. Low cost flexible electronic devices play a critical role in these endeavors. This course will trace the evolution of reliable, large-area, flexible electronics and associated technologies, and will cover fabrication approaches such as chip attachment, thin-film devices, and nanoscale self-assembled and printed device based coatings. Additionally, fundamentals of state of the art fabrication techniques including vapor phase processing and direct fabrication approaches such as printing with aerosols and particle-based inks featuring advanced electronic materials to enable flexible electronic devices will be presented.